Local tshuaj loog

Feb 17, 2023

Tso lus

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Kev xaiv ntawm tshuaj loog hauv zos yog feem ntau raws li nws cov pharmacokinetics. Qhov chaw ntawm kev tswj hwm thiab txoj hauv kev ntawm kev tswj hwm tuaj yeem cuam tshuam cov khoom ntawm cov tshuaj. Feem ntau cov tshuaj loog hauv zos ua sai sai thaum muab parenterally rau infiltration tshuaj loog, qhov ceev tshaj plaws yog lidocaine (0.5-1 min), ua raws li prilocaine (1-2 min). Lub sij hawm nruab nrab pib rau cov neeg sawv cev ntxiv yog 3-5 feeb. Tsuas yog tetracaine, uas yuav siv sijhawm li 15 feeb. Epidurals siv sijhawm ntev dua los ua haujlwm, nrog rau feem ntau cov tshuaj loog hauv zos siv qhov nruab nrab li ntawm 5-15 feeb los ua haujlwm. Procaine (15-25 feeb), tetracaine (20-30 feeb), thiab bupivacaine (10-20 feeb) yog cov qeeb qeeb me ntsis thaum muab epidurally dua li lwm cov tshuaj.

Lub sijhawm ua haujlwm ntawm kev txhaj tshuaj loog yog qhov tseem ceeb hauv lawv cov kev xaiv rau kev siv ntau yam txheej txheem. Procaine thiab chloroprocaine yog cov tshuaj nrog qhov pib ua haujlwm luv tshaj plaws ({{{0}}}.25-0.5 teev), ua raws li lidocaine, mepivacaine, thiab prilocaine, uas tau siv sijhawm ntev dua me ntsis. (0.5-1.5 teev ). Cov tshuaj ua haujlwm ntev suav nrog tetracaine (2-3 teev), bupivacaine (2-4 teev), etidocaine (2-3 teev), thiab ropivacaine. Ropivacaine muaj lub sijhawm ntev ntawm 8-13 teev thaum siv rau cov hlab ntsha peripheral, tab sis tsuas yog 2.

Thaum siv cov tshuaj pleev ib ce, cov tshuaj loog hauv zos ncav cuag lawv cov txiaj ntsig siab ntawm ntau lub sijhawm thaum siv rau cov mucous membranes. Benzocaine tau ceev tshaj plaws (1 feeb), ua raws li lidocaine=cocaine