Dabigatran Etexilate Mesylate

CAS Nr: 872728-81-9

Cov mis mos molecular: C35H45N7O8S

Molecular Luj: 723.85

EINECS Number: 828-727-6

Dabigatranetexilatemesylate(BIBR1048MS; qhov ncauj;10,20and50mg/kgforratsand1,2.5and5mg/kgformonkeys)hasdose-andtime-dependentanticoagulanteffectsandhasmaximumeffectsbet1ministration.Daim ntawv qhia latemaximallyandsignificantly prolongspartialthromboplastintime(aPTT) rau 25.2,38.4and78.3sin30minafter10,20and50mChemicalbookg /kgoraldoses, ntsig txog.DabigatranetexilatemesylatemaximallyprolongstheaPTTto34.3s,44.0s,and63.0s,feem ntau,2hafter1,2.5or5mg/kgdosesinthemonkey.AnimalModel:Malerats({{33}sothers)g 0,20 thiab 50 mg /kgforratsand1,2.5and5mg/kgformonkeysAdministration: OralResult:Haddose-andtime-dependentanticoagulanteffects.

Melting point: >125 degree
Cia Tej yam kev mob: Lub tub yees
Solubility: DMSO (me ntsis, rhaub), Methanol (me ntsis)
Daim ntawv: Khoom
Xim: Dawb rau daj daj

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